Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.31 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.31 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789105 | 1.00 | CHRM1 (0.31) | CHRM1GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL602982 | 0.85 | GNAI3 (0.35) | CHRM1GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL602981 | 0.85 | GNAI3 (0.35) | CHRM1GNAI3GNAO1GNAI1NPC1 | |
| Hydrochloric Acid SCHEMBL601271 | 0.83 | GNAI3 (0.38) | CHRM1GNAI3GNAO1GNAI1NPC1 | |
| Hydrochloric Acid SCHEMBL601270 | 0.83 | GNAI3 (0.38) | CHRM1GNAI3GNAO1GNAI1NPC1 | |
| SCHEMBL602533 | 0.82 | CHRM1 (0.37) | CHRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL602532 | 0.82 | CHRM1 (0.37) | CHRM1GNAI3GNAO1GNAI1 | |
| SCHEMBL23329136 | 0.82 | — | — | |
| SCHEMBL1241366 | 0.82 | — | — | |
| SCHEMBL1241364 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008119721-A1 | COMPOUNDS WHICH HAVE ACTIVITY AT M1 RECEPTOR AND THEIR USES IN MEDICINE | GLAXO GROUP LIMITED (GB) | 2008-10-09 | — | — | WO | disclosed |