Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PSMD14 | O00487 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | VCP | P55072 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789328 | 1.00 | MEN1 (0.36) | MEN1KMT2APSMD14L3MBTL1MITF | |
| SCHEMBL3750991 | 0.88 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3750998 | 0.88 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL3750983 | 0.88 | KMT2A (0.37) | MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL121200 | 0.72 | VCP (0.49) | MEN1KMT2APSMD14L3MBTL1MITF | |
| SCHEMBL145009 | 0.72 | VCP (0.49) | MEN1KMT2APSMD14L3MBTL1MITF | |
| SCHEMBL18579270 | 0.68 | MEN1 (0.39) | MEN1KMT2APSMD14L3MBTL1MITF | |
| SCHEMBL18579272 | 0.68 | MEN1 (0.39) | MEN1KMT2APSMD14L3MBTL1MITF | |
| SCHEMBL18590417 | 0.67 | MEN1 (0.43) | MEN1KMT2APSMD14L3MBTL1MITF | |
| SCHEMBL19559419 | 0.67 | MEN1 (0.38) | MEN1KMT2APSMD14L3MBTL1MITF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1919854-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2008-05-14 | — | — | EP | disclosed |
| WO-2007027651-A2 | PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF DIPEPTIDYL PEPTIDASE-IV (DPP-IV) | ABBOTT LABORATORIES (US) | 2007-03-08 | — | — | WO | disclosed |