Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 5/20 | 0.36 |
| ▸ | PPARA | Q07869 | 5/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.36 |
| ▸ | WNT3A | P56704 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 3/20 | 0.32 |
| ▸ | CTSA | P10619 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.32 |
| ▸ | RAB9A | P51151 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.32 |
| ▸ | THRA | P10827 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.32 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789427 | 0.87 | PPARD (0.49) | PPARDPPARAPPARGMAPT | |
| SCHEMBL2466122 | 0.85 | PPARD (0.45) | PPARDPPARAPPARGALDH1A1MAPT | |
| SCHEMBL2464421 | 0.85 | PPARD (0.45) | PPARDPPARAPPARGWNT3AS1PR1 | |
| SCHEMBL2466105 | 0.85 | PPARD (0.37) | PPARDPPARAPPARGWNT3AS1PR1 | |
| SCHEMBL2464201 | 0.84 | PPARD (0.49) | PPARDPPARAPPARGWNT3ACTSA | |
| SCHEMBL2467481 | 0.83 | PPARD (0.38) | PPARDPPARAPPARGWNT3AS1PR1 | |
| SCHEMBL2463130 | 0.83 | WNT3A (0.36) | PPARDPPARAPPARGWNT3ACTSA | |
| SCHEMBL4788692 | 0.83 | PPARD (0.34) | PPARDPPARAPPARGWNT3AALDH1A1 | |
| SCHEMBL1765993 | 0.82 | PPARD (0.34) | PPARDPPARAPPARGWNT3AS1PR1 | |
| SCHEMBL2468551 | 0.82 | PPARA (0.41) | PPARDPPARAPPARGWNT3AS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008154023-A1 | NOVEL USES OF PPAR DELTA AGONISTS | CERENIS THERAPEUTICS S.A. (FR) | 2008-12-18 | — | — | WO | disclosed |