Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.45 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | TGM2 | P21980 | 4/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 4/20 | 0.33 |
| ▸ | CNR2 | P34972 | 4/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5693336 | 0.92 | TSHR (0.52) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL7754139 | 0.89 | ALDH1A1 (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL12314771 | 0.89 | TSHR (0.48) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL5693410 | 0.88 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL485490 | 0.87 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL5693415 | 0.87 | TSHR (0.46) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL138083 | 0.86 | ALDH1A1 (0.54) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL27917330 | 0.86 | TSHR (0.45) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL28954953 | 0.84 | TSHR (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 | |
| SCHEMBL1423564 | 0.84 | ALDH1A1 (0.43) | TSHRALDH1A1MAPK1TDP1ZDHHC20 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009056955-A1 | AMINE-BEARING PHOSPHOLIPIDS (ABPS), THEIR SYNTHESIS AND USE | UNIVERSITY OF BASEL (CH) | 2009-05-07 | — | — | WO | disclosed |
| WO-2008118626-A9 | INHIBITORS OF JNK AND METHODS FOR IDENTIFYING INHIBITORS OF JNK | BURNHAM INST MEDICAL RESEARCH (US) | 2008-12-18 | — | — | WO | disclosed |
| WO-2008118626-A2 | INHIBITORS OF JNK AND METHODS FOR IDENTIFYING INHIBITORS OF JNK | BURNHAM INSTITUTE FOR MEDICAL RESEARCH (US) | 2008-10-02 | — | — | WO | disclosed |