Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | AHR | P35869 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.35 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16132504 | 0.83 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1MAPTAHRCHRM2 | |
| SCHEMBL3299722 | 0.82 | SMN1; SMN2 (0.44) | SMN1; SMN2L3MBTL1MAPTCHRM2ALDH1A1 | |
| SCHEMBL21742045 | 0.80 | SMN1; SMN2 (0.47) | SMN1; SMN2L3MBTL1MAPTAHRCHRM2 | |
| SCHEMBL21742319 | 0.79 | CHRM2 (0.43) | SMN1; SMN2L3MBTL1MAPTCHRM2ALDH1A1 | |
| SCHEMBL21742149 | 0.79 | SMN1; SMN2 (0.41) | SMN1; SMN2L3MBTL1MAPTAHRCHRM2 | |
| SCHEMBL23364963 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM2ALDH1A1 | |
| SCHEMBL12717402 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM2ALDH1A1 | |
| SCHEMBL29828412 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM2ALDH1A1 | |
| SCHEMBL30471943 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM2ALDH1A1 | |
| SCHEMBL26835113 | 0.78 | SMN1; SMN2 (0.57) | SMN1; SMN2L3MBTL1AHRCHRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3611164-A1 | PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT | Mitsui Chemicals Agro, Inc. (JP) | 2020-02-19 | — | — | EP | disclosed |
| US-9969858-B2 | Metalloinsertor conjugates | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2018-05-15 | — | — | US | disclosed |
| US-20160222043-A1 | METALLOINSERTOR CONJUGATES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2016-08-04 | — | — | US | disclosed |
| WO-2008075380-A2 | PROCESS FOR THE PREPARATION OF THIAZOLIDINE DERIVATIVES | IND-SWIFT LABORATORIES LIMITED (IN) | 2008-06-26 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160222043-A1 | METALLOINSERTOR CONJUGATES | MSH2, MSH6, LIG1 | SMN1; SMN2 285/4885L3MBTL1 8/4885MAPT 3668/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.