Sugi Predict
/ Targets
/ MSH6
Top predicted compounds (top 20 by supporting neighbours, then confidence)
| Compound | Confidence | Supporting neighbours |
|---|
Clinical trials — most relevant to MSH6 by text similarity (a relevance ranking, not an exhaustive list)
| Trial | Phase | Status |
|---|
| A Phase II Study of Tegafur-Uracil as Maintenance Chemotherapy in Patients With Stage II of Colon Cancer |
PHASE4 | UNKNOWN |
| International Cooperative Phase III Trial of the HIT-HGG Study Group (HIT-HGG-2013) |
PHASE3 | UNKNOWN |
| mFOLFOX6 + Bevacizumab + PD-1 Monoclonal Antibody Vs. mFOLFOX6 in Locally Advanced pMMR/MSS CRC |
PHASE3 | RECRUITING |
| Real-world Trial of Individualized Precision Oncology |
PHASE2 | NOT_YET_RECRUITING |
| Phase I/II Study of the Combination Immunotherapy Regimen: SX-682, TriAdeno Vaccine, Retifanlimab and IL-15 Agonist N-803 (STAR15) for Metastatic Colorectal Cancer (mCRC) |
PHASE1/PHASE2 | RECRUITING |
| Olaparib Maintenance in Patients With MCRPC After Docetaxel Treatment Reaching Partial or Stable Response (IMANOL) |
PHASE2 | COMPLETED |
| A Phase II Study of Tislelizumab as Adjuvant Therapy for Patients With Stage Ⅱ and Stage Ⅲ Colon Cancer and dMMR/MSI. |
PHASE2 | NOT_YET_RECRUITING |
| Study of Induction PD-1 Blockade (Nivolumab) in Patients With Surgically Complete Resectable Mismatch Repair Deficient Endometrial Cancer (NIVEC) |
PHASE2 | RECRUITING |
| Clinical Trial of All-trans-retinoic Acid, Bevacizumab and Atezolizumab in Colorectal Cancer |
PHASE2 | ACTIVE_NOT_RECRUITING |
| Node-Sparing Short-Course Radiotherapy Plus First-Line Therapy and PD-1 Inhibitor in Unresectable/Metastastic pMMR/MSS Gastric Cancer (MODIFI-GC) |
PHASE2 | NOT_YET_RECRUITING |
| Node-Sparing Low-Dose Radiotherapy Concurrent With Chemotherapy and PD-1 Inhibitor in pMMR/MSS High-Risk Locally Advanced Colon Cancer: A Prospective, Single-Arm, Phase II Trial |
PHASE2 | RECRUITING |
| Safety and Efficacy of PD-1 ± mFOLFOX6 Neoadjuvant Therapy in Local Advanced sMPCC |
PHASE2 | RECRUITING |
| Study of Relatlimab and Nivolumab (Opdualag) in Replication Repair Deficient HGG and DIPG |
PHASE2 | NOT_YET_RECRUITING |
| Naproxen in Preventing DNA Mismatch Repair Deficient Colorectal Cancer in Patients With Lynch Syndrome |
PHASE1 | COMPLETED |
| Testing the Combination of Two Immunotherapy Drugs (Nivolumab and Ipilimumab) in Children, Adolescent, and Young Adult Patients With Relapsed/Refractory Cancers That Have an Increased Number of Genetic Changes, The 3CI Study |
PHASE1 | WITHDRAWN |
| Lynch Syndrome in Colorectal Cancer Surgery |
nan | NOT_YET_RECRUITING |
| Virtual Prostate Biopsy Protocol for Patients on Active Surveillance and at Risk of Prostate Cancer |
nan | WITHDRAWN |
| Faecal Microbiota Characterization in Lynch Syndrome (LS) Patients With or Without Colorectal Neoplasia |
nan | UNKNOWN |
| Pembrolizumab (MK-3475) in Patients With Recurrent Malignant Glioma With a Hypermutator Phenotype |
nan | ACTIVE_NOT_RECRUITING |
| Current Microsatellite Stability Results in Colon Cancer |
nan | NOT_YET_RECRUITING |
| Patient-derived Glioma Stem Cell Organoids |
nan | ACTIVE_NOT_RECRUITING |
| Cohort Evaluation of Body Fluids Early Detection of Cancer in High-risk Individuals |
nan | RECRUITING |
| Videocapsule Endoscopy in Lynch Syndrome |
nan | RECRUITING |
| Predictive Value of PREMM5, MMRpredict, and Universal Tumor Screening for Lynch Syndrome in Vietnam |
nan | NOT_YET_RECRUITING |
| How Epigenetic Changes in hMLH1 Connect Lab Research With Diagnosis in Gastric Cancer |
nan | RECRUITING |
| National Cohort of Colorectal Cancers With Microsatellite Instability |
nan | ACTIVE_NOT_RECRUITING |
| Diagnosis of Lynch Syndrome Based on Next-generation Sequencing in Colorectal Cancer |
nan | COMPLETED |
| Influence of the Surgical Technique Used for Colectomies on the Concentration of Circulating Tumor DNA and the Presence of Circulating Tumor Cells: Comparison of the no Touch Technic With Either First Clamping of the Mesenteric Vessels or First Mobilization of the Tumor Followed by Clamping. |
nan | UNKNOWN |
| Frequency of Endometrial Cancer Precursors Associated with Lynch Syndrome |
nan | COMPLETED |
| ACT-GEN (Adherence And Care Tracking In GENetic Cancer Syndromes) |
nan | NOT_YET_RECRUITING |
Related proteins — ESM-2 sequence neighbours (a MSH6 binder may also engage these)