Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A7 | Q99884 | 17/20 | 0.74 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.59 |
| ▸ | TSHR | P16473 | 1/20 | 0.59 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3575523 | 0.90 | SLC6A7 (0.92) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3578242 | 0.86 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL5823601 | 0.84 | SLC6A7 (0.62) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL14182187 | 0.84 | SLC6A7 (0.72) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4789639 | 0.83 | SLC6A7 (0.68) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL4391715 | 0.81 | SLC6A7 (0.90) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3583012 | 0.78 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3572601 | 0.77 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHRL3MBTL1 | |
| SCHEMBL3586157 | 0.76 | SLC6A7 (1.00) | SLC6A7SLC6A3ALDH1A1TSHR | |
| SCHEMBL3779038 | 0.76 | SLC6A7 (0.79) | SLC6A7SLC6A3ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1893212-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | Lexicon Pharmaceuticals, Inc. (US) | 2008-03-05 | — | — | EP | claimed |
| WO-2006124748-A2 | MULTICYCLIC COMPOUNDS AND METHODS OF THEIR USE | LEXICON GENETICS INCORPORATED (US) | 2006-11-23 | — | — | WO | claimed |