SCHEMBL4789638

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4790459	0.91	TDP1 (0.47)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4758752	0.90	TDP1 (0.46)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4789173	0.89	GRM5 (0.40)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4788797	0.89	TDP1 (0.45)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4790147	0.89	TDP1 (0.43)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4756488	0.87	TDP1 (0.48)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4789912	0.86	TDP1 (0.43)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4788101	0.85	ESR2 (0.48)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL4789671	0.85	ESR2 (0.55)	POLBESR2ALDH1A1ESR1TDP1
	SCHEMBL5112030	0.84	ALDH1A1 (0.49)	POLBESR2ALDH1A1ESR1TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.