Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.57 |
| ▸ | POLB | P06746 | 2/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.44 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HBB | P68871 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3619161 | 0.87 | MYC (0.53) | MYCPOLBALDH1A1MAPK1MEN1 | |
| SCHEMBL1707748 | 0.84 | MYC (0.58) | MYCALDH1A1MAPK1MEN1LMNA | |
| SCHEMBL1590359 | 0.84 | MYC (0.60) | MYCALDH1A1MAPK1KMT2AFOLH1 | |
| SCHEMBL28483244 | 0.81 | MYC (0.54) | MYCPOLBALDH1A1MAPK1MEN1 | |
| SCHEMBL27663826 | 0.79 | MYC (0.61) | MYCALDH1A1LMNAFOLH1MAPT | |
| SCHEMBL15136711 | 0.79 | MYC (0.56) | MYCPOLBALDH1A1MAPK1MEN1 | |
| SCHEMBL604636 | 0.79 | MYC (0.70) | MYCPOLBALDH1A1MEN1LMNA | |
| SCHEMBL28830921 | 0.79 | MYC (0.55) | MYCPOLBALDH1A1MAPK1KMT2A | |
| SCHEMBL28690629 | 0.78 | MYC (0.64) | MYCPOLBALDH1A1MAPK1MEN1 | |
| Hydrochloric Acid SCHEMBL29281801 | 0.77 | MYC (0.53) | MYCPOLBALDH1A1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008124575-A1 | RENIN INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-10-16 | — | — | WO | disclosed |