Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MYC | P01106 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4789889 | 0.87 | MYC (0.57) | MYCALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL1590359 | 0.84 | MYC (0.60) | MYCALDH1A1MAPK1KMT2AFOLH1 | |
| SCHEMBL27663826 | 0.83 | MYC (0.61) | MYCALDH1A1MAPTFOLH1LMNA | |
| SCHEMBL9450908 | 0.83 | FOLH1 (0.47) | MYCALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL29823919 | 0.83 | FOLH1 (0.47) | MYCALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL22684102 | 0.80 | MYC (0.45) | MYCALDH1A1MAPK1MEN1MAPT | |
| SCHEMBL6142488 | 0.80 | MYC (0.57) | MYCALDH1A1MAPK1MEN1MAPT | |
| Phthalic Acid SCHEMBL9869587 | 0.79 | ALDH1A1 (0.50) | MYCALDH1A1MEN1KMT2ALMNA | |
| SCHEMBL28830921 | 0.79 | MYC (0.55) | MYCALDH1A1MAPK1KMT2AFOLH1 | |
| SCHEMBL6316188 | 0.79 | MMP2 (0.55) | MYCALDH1A1MAPK1MEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8202989-B2 | One step process for the preparation of substituted 5, 10-dihydrodibenzo [b,e][1, 4]diazepine-11-ones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-19 | — | — | US | claimed |
| US-20100228023-A1 | ONE STEP PROCESS FOR THE PREPARATION OF SUBSTITUTED 5, 10-DIHYDRODIBENZO [b,e][1, 4]DIAZEPINE-11-ONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-09-09 | — | — | US | claimed |
| US-8202989-B2 | One step process for the preparation of substituted 5, 10-dihydrodibenzo [b,e][1, 4]diazepine-11-ones | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2012-06-19 | — | — | US | disclosed |
| US-20100228023-A1 | ONE STEP PROCESS FOR THE PREPARATION OF SUBSTITUTED 5, 10-DIHYDRODIBENZO [b,e][1, 4]DIAZEPINE-11-ONES | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100228023-A1 | ONE STEP PROCESS FOR THE PREPARATION OF SUBSTITUTED 5, 10-DIHYDRODIBENZO [b,e][1, 4]DIAZEPINE-11-ONES | BBOX1, CYP1B1, CYP4B1 | MYC 3670/4885ALDH1A1 18/4885MAPK1 796/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.