Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDR | P35968 | 16/20 | 0.67 |
| ▸ | FLT3 | P36888 | 9/20 | 0.64 |
| ▸ | GSK3B | P49841 | 9/20 | 0.64 |
| ▸ | PDGFRB | P09619 | 5/20 | 0.64 |
| ▸ | IGF1R | P08069 | 4/20 | 0.64 |
| ▸ | KIT | P10721 | 4/20 | 0.64 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.64 |
| ▸ | FLT1 | P17948 | 4/20 | 0.64 |
| ▸ | FLT4 | P35916 | 4/20 | 0.64 |
| ▸ | TEK | Q02763 | 4/20 | 0.64 |
| ▸ | EGFR | P00533 | 3/20 | 0.64 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.64 |
| ▸ | PLK4 | O00444 | 1/20 | 0.64 |
| ▸ | AURKA | O14965 | 1/20 | 0.64 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.64 |
| ▸ | ABL1 | P00519 | 1/20 | 0.64 |
| ▸ | INSR | P06213 | 1/20 | 0.64 |
| ▸ | MET | P08581 | 1/20 | 0.64 |
| ▸ | CDK4 | P11802 | 1/20 | 0.64 |
| ▸ | SRC | P12931 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10629414 | 0.84 | KDR (0.52) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL27941836 | 0.84 | KDR (0.67) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL27983199 | 0.83 | PDE4B (0.52) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL1155691 | 0.83 | KDR (0.63) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL4752042 | 0.82 | ALDH1A1 (0.54) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL1155579 | 0.80 | KDR (0.59) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL3823447 | 0.79 | STK10 (0.66) | GSK3B | |
| Maleimide SCHEMBL1155440 | 0.79 | KDR (1.00) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL1155976 | 0.78 | KDR (0.63) | KDRFLT3GSK3BPDGFRBIGF1R | |
| SCHEMBL1155542 | 0.77 | KDR (1.00) | KDRFLT3GSK3BPDGFRBFLT4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008140251-A2 | CYCLOOXYGENASE-2 INHIBITORS | UNIVERSITY-INDUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY (KR) | 2008-11-20 | — | — | WO | disclosed |