Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD4 | P21917 | 15/20 | 0.53 |
| ▸ | HTR2A | P28223 | 11/20 | 0.53 |
| ▸ | DRD2 | P14416 | 12/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4579442 | 0.93 | DRD4 (0.54) | DRD4HTR2ADRD2HDAC1 | |
| SCHEMBL4578949 | 0.91 | HDAC1 (0.58) | DRD4HTR2ADRD2HDAC1 | |
| SCHEMBL4578946 | 0.91 | HDAC1 (0.58) | DRD4HTR2ADRD2HDAC1 | |
| SCHEMBL14155917 | 0.89 | DRD4 (0.49) | DRD4HTR2ADRD2HDAC1 | |
| SCHEMBL4789471 | 0.84 | DRD4 (0.48) | DRD4HTR2ADRD2HDAC1 | |
| SCHEMBL4579458 | 0.81 | DRD4 (0.57) | DRD4HTR2ADRD2 | |
| SCHEMBL4578634 | 0.78 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL4578628 | 0.78 | HDAC1 (0.69) | HDAC1 | |
| SCHEMBL4580902 | 0.75 | DRD4 (0.57) | DRD4HTR2ADRD2HDAC1 | |
| SCHEMBL4578400 | 0.74 | HDAC1 (0.69) | DRD4HTR2ADRD2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2007720-A1 | BENZAMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | Methylgene, Inc. (CA) | 2008-12-31 | — | — | EP | disclosed |
| WO-2007118137-A1 | BENZAMIDE DERIVATIVES AS INHIBITORS OF HISTONE DEACETYLASE | METHYLGENE INC. (CA) | 2007-10-18 | — | — | WO | disclosed |