Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | GRM5 | P41594 | 4/20 | 0.38 |
| ▸ | DYRK1A | Q13627 | 4/20 | 0.36 |
| ▸ | DYRK2 | Q92630 | 4/20 | 0.36 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.36 |
| ▸ | CDK2 | P24941 | 3/20 | 0.36 |
| ▸ | CDK5 | Q00535 | 3/20 | 0.36 |
| ▸ | CDK5R1 | Q15078 | 3/20 | 0.36 |
| ▸ | DYRK1B | Q9Y463 | 3/20 | 0.36 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.34 |
| ▸ | EIF4A3 | P38919 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DYRK3 | O43781 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 2/20 | 0.33 |
| ▸ | CDK9 | P50750 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790002 | 0.97 | HPGD (0.43) | HPGDKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL4789402 | 0.94 | GRM5 (0.41) | HPGDKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL4790167 | 0.87 | TDP1 (0.53) | HPGDKDM4EMEN1KMT2ATDP1 | |
| SCHEMBL4790271 | 0.87 | NPC1 (0.41) | HPGDGRM5ALDH1A1LMNA | |
| SCHEMBL4756503 | 0.87 | GRM5 (0.44) | HPGDKDM4ETDP1GRM5ALDH1A1 | |
| SCHEMBL4790148 | 0.86 | ALDH1A1 (0.42) | HPGDKDM4ETDP1GRM5P2RX7 | |
| SCHEMBL4755882 | 0.86 | GRM5 (0.42) | HPGDKDM4ETDP1GRM5ALDH1A1 | |
| SCHEMBL4790072 | 0.86 | GRM5 (0.44) | HPGDKDM4ETDP1GRM5ALDH1A1 | |
| SCHEMBL4789879 | 0.85 | GRM5 (0.43) | HPGDKDM4ETDP1GRM5ALDH1A1 | |
| SCHEMBL4758582 | 0.85 | GRM5 (0.46) | HPGDKDM4ETDP1GRM5ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008015271-A1 | PYRAZOLOPYRIMIDINES, A PROCESS FOR THEIR PREPARATION AND THE USE AS A MEDICINE | MERZ PHARMA GMBH & CO. KGAA (DE) | 2008-02-07 | — | — | WO | disclosed |