Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 4/20 | 0.50 |
| ▸ | DRD2 | P14416 | 1/20 | 0.49 |
| ▸ | DRD4 | P21917 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4284928 | 0.77 | BCHE (0.58) | BCHEACHEDRD2DRD4 | |
| SCHEMBL9381126 | 0.77 | DRD2 (0.52) | BCHEACHEDRD2DRD4 | |
| SCHEMBL4696031 | 0.77 | BCHE (0.55) | BCHEACHEDRD2DRD4 | |
| SCHEMBL4790506 | 0.76 | DCUN1D1 (0.44) | BCHEACHE | |
| SCHEMBL11095982 | 0.75 | BCHE (0.58) | BCHEACHE | |
| Hydrochloric Acid SCHEMBL11128760 | 0.74 | BCHE (0.59) | BCHEACHE | |
| SCHEMBL7501904 | 0.74 | DRD2 (0.63) | BCHEACHEDRD2DRD4 | |
| SCHEMBL4289978 | 0.73 | BCHE (0.69) | BCHEACHEDRD2DRD4 | |
| Hydrochloric Acid SCHEMBL9381094 | 0.73 | BCHE (0.69) | BCHEACHEDRD2DRD4 | |
| SCHEMBL9382105 | 0.72 | DRD2 (0.54) | BCHEACHEDRD2DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1910380-A1 | OXAZOLOPYRIDINE DERIVATIVES AS SIRTUIN MODULATORS | Sirtris Pharmaceuticals, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007019417-A1 | OXAZOLOPYRIDINE DERIVATIVES AS SIRTUIN MODULATORS | SIRTRIS PHARMACEUTICALS, INC. (US) | 2007-02-15 | — | — | WO | disclosed |