Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 4/20 | 0.37 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ECE1 | P42892 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.33 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31759207 | 0.87 | RAB9A (0.42) | RAB9ALMNAACEACE2ALDH1A1 | |
| SCHEMBL6017672 | 0.86 | GBA2 (0.39) | L3MBTL1RAB9AGBA2SMN1; SMN2LMNA | |
| SCHEMBL7672219 | 0.80 | RAB9A (0.50) | L3MBTL1RAB9AGBA2SMN1; SMN2LMNA | |
| SCHEMBL5491802 | 0.80 | RAB9A (0.50) | L3MBTL1RAB9AGBA2SMN1; SMN2LMNA | |
| SCHEMBL4748923 | 0.80 | RAB9A (0.50) | L3MBTL1RAB9AGBA2SMN1; SMN2LMNA | |
| SCHEMBL13066774 | 0.79 | HDAC8 (0.39) | L3MBTL1ALDH1A1MEN1KMT2AATM | |
| SCHEMBL31759059 | 0.78 | TSHR (0.39) | RAB9ASMN1; SMN2LMNAACEACE2 | |
| SCHEMBL8445034 | 0.78 | ACE (0.48) | L3MBTL1GBA2SMN1; SMN2LMNAPOLB | |
| SCHEMBL10434958 | 0.78 | ACE (0.48) | L3MBTL1GBA2SMN1; SMN2LMNAPOLB | |
| SCHEMBL2634067 | 0.77 | RAB9A (0.62) | L3MBTL1RAB9ASMN1; SMN2LMNAACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |