Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | G6PD | P11413 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.41 |
| ▸ | PER2 | O15055 | 1/20 | 0.41 |
| ▸ | DDB1 | Q16531 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20329795 | 1.00 | KMT2A (0.47) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL17779651 | 0.95 | MEN1 (0.46) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL266004 | 0.89 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL12015718 | 0.89 | MEN1 (0.50) | KMT2AMEN1NPC1RAB9AALDH1A1 | |
| SCHEMBL13887446 | 0.83 | AKR1C3 (0.40) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14835561 | 0.83 | ALDH1A1 (0.44) | KMT2AMEN1ALDH1A1USP2MAPT | |
| SCHEMBL1829503 | 0.82 | KMT2A (0.52) | KMT2ANPC1ALDH1A1L3MBTL1 | |
| SCHEMBL8224932 | 0.81 | ALDH1A1 (0.47) | KMT2AMEN1ALDH1A1SMN1; SMN2L3MBTL1 | |
| SCHEMBL22365622 | 0.80 | ALDH1A1 (0.50) | KMT2AMEN1ALDH1A1POLBMAPT | |
| SCHEMBL20334085 | 0.79 | KMT2A (0.44) | KMT2AMEN1NPC1RAB9AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2450349-A1 | N-(1-PHENYL-2-OXO-3-PIPERIDYL)SULPHONAMIDE LIBRARIES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2012-05-09 | — | — | EP | disclosed |
| EP-2447251-A1 | N-(1-PHENYL-2-OXO-3-PIPERIDYL SULPHONAMIDE LIBRARIES FOR DRUG DISCOVERY | Institut Univ. de Ciència i Tecnologia, S.A. (ES) | 2012-05-02 | — | — | EP | disclosed |
| WO-2010150204-A1 | N-(2-OXO-1-PHENYLPIPERIDIN-3-YL) SULFONAMIDES FOR THE IDENTIFICATION OF BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY | INSTITUT UNIV. DE CIÈNCIA I TECNOLOGIA, S.A. (ES) | 2010-12-29 | — | — | WO | disclosed |