SCHEMBL479132

SCHEMBL479132

CCC(CC1CO1)OC(CC)CC1CO1

nearest known ligand 0.35

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.35
MAPK1 P28482 1/20 0.35
ALDH1A1 P00352 5/20 0.35
SMN1; SMN2 Q16637 1/20 0.34
TDP1 Q9NUW8 2/20 0.32
TP53 P04637 1/20 0.31
CYP3A4 P08684 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17629221 0.85 ALDH1A1 (0.36) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL7157277 0.84
SCHEMBL2331883 0.82 ALDH1A1 (0.41) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL3983470 0.82
SCHEMBL11394803 0.79 ALDH1A1 (0.39) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL3238846 0.79 ALDH1A1 (0.50) TSHRMAPK1ALDH1A1SMN1; SMN2TDP1
SCHEMBL27771471 0.77 ALDH1A1 (0.31) ALDH1A1
SCHEMBL7637759 0.77 HTT (0.37) TSHRALDH1A1SMN1; SMN2TP53
SCHEMBL6925925 0.77 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2TDP1
SCHEMBL3231987 0.76 ALDH1A1 (0.48) ALDH1A1SMN1; SMN2TDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 111 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3325540-B1 ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES MOMENTIVE PERFORMANCE MAT GMBH (DE) 2025-07-02 EP claimed
US-11535751-B2 Asymmetrically substituted polyorganosiloxane derivatives MOMENTIVE PERFORMANCE MATERIALS GMBH 2022-12-27 US claimed
CN-108026279-B Asymmetrically substituted polyorganosiloxane derivatives 莫门蒂夫性能材料有限公司 2022-04-01 CN claimed
CN-108026372-B Modified filler particles and silicone compositions containing the same 莫门蒂夫性能材料有限公司 2022-03-15 CN claimed
US-20180371248-A1 ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES CITIBANK, N.A., AS ADMINISTRATIVE AGENT 2018-12-27 US claimed
US-20180208718-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS INC. 2018-07-26 US claimed
EP-3325557-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME Momentive Performance Materials GmbH (DE) 2018-05-30 EP claimed
EP-3325540-A1 ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES Momentive Performance Materials GmbH (DE) 2018-05-30 EP claimed
CN-108026372-A Modified filler particles and the silicon composition comprising the particle 莫门蒂夫性能材料有限公司 2018-05-11 CN claimed
WO-2017012714-A1 ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-01-26 WO claimed
WO-2017012715-A1 MODIFIED FILLER PARTICLES AND SILICONE COMPOSITIONS COMPRISING THE SAME MOMENTIVE PERFORMANCE MATERIALS GMBH (DE) 2017-01-26 WO claimed
US-20100121016-A1 LOW REFRACTIVE INDEX HYBRID OPTICAL CLADDING AND ELECTRO-OPTIC DEVICES MADE THEREFROM GIGOPTIX, INC. (US) 2010-05-13 US claimed
EP-0382931-B1 Polyether, its preparation and use HUELS CHEMISCHE WERKE AG (DE) 1993-11-18 EP claimed
US-12441909-B2 Hydrophobic coating compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2025-10-14 US disclosed
EP-3325540-B1 ASYMMETRICALLY SUBSTITUTED POLYORGANOSILOXANE DERIVATIVES MOMENTIVE PERFORMANCE MAT GMBH (DE) 2025-07-02 EP disclosed
CN-115485326-B Functionalized silica particles and uses thereof 迈图高新材料有限责任公司 2025-04-15 CN disclosed
EP-0765911-A2 Reinforced biodegradable plastics BAYER AG (DE) 1997-04-02 EP disclosed
EP-0761689-A1 Thermoplastic biodegradable polysaccharide derivatives, process for their preparation and their uses WOLFF WALSRODE AG (DE) 1997-03-12 EP disclosed
EP-0668293-A2 Thermoplastic biodegradable polysaccharide derivates, process for obtaining the same and their uses WOLFF WALSRODE AG (DE) 1995-08-23 EP disclosed
EP-0626392-A1 Thermoplastic graft copolymers ether-ester of cellulose and process for their preparation WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) 1994-11-30 EP disclosed