Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 5/20 | 0.41 |
| ▸ | ALOX5 | P09917 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.40 |
| ▸ | PRNP | P04156 | 1/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | F11 | P03951 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4792508 | 0.96 | PTGS2 (0.45) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL17922122 | 0.95 | KDM4E (0.44) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL4792192 | 0.88 | MEN1 (0.49) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL4792280 | 0.86 | KDM4E (0.40) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL15385011 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL4792510 | 0.84 | MEN1 (0.50) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL3533863 | 0.83 | KDM4E (0.47) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL4792565 | 0.83 | PTGS2 (0.44) | KDM4EALDH1A1HPGDMEN1KMT2A | |
| SCHEMBL4790729 | 0.82 | MEN1 (0.51) | KDM4EALDH1A1HPGDALOX5MEN1 | |
| SCHEMBL12940112 | 0.81 | KDM4E (0.41) | KDM4EALDH1A1HPGDALOX5MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2632261-B1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS INC (US) | 2016-07-13 | — | — | EP | disclosed |
| WO-2012058125-A1 | INHIBITORS OF HEPATITIS C VIRUS | PRESIDIO PHARMACEUTICALS, INC. (US) | 2012-05-03 | — | — | WO | disclosed |