SCHEMBL4792502

SCHEMBL4792502

[C]1=CNc2ccccc2NC1

nearest known ligand 0.30

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4577839 0.68 GAA (0.36) ALOX15HSD17B10
SCHEMBL2655668 0.68 PLAU (0.42) ALOX15HSD17B10
SCHEMBL38709 0.67 ALOX15 (0.32) ALOX15HSD17B10
SCHEMBL3032778 0.64
SCHEMBL5567 0.64 ALOX15 (0.33) ALOX15HSD17B10
SCHEMBL123812 0.63 GAA (0.54) ALOX15HSD17B10
SCHEMBL30549 0.63
SCHEMBL29408147 0.63 GAA (0.54) ALOX15HSD17B10
SCHEMBL29144954 0.63 GAA (0.54) ALOX15HSD17B10
SCHEMBL3037604 0.62 GAA (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1641799-B1 IMIDAZO-PYRIDAZINONE DERIVATIVES AND IMIDAZO-PYRIDONE DERIVATIVES, PRODUCTION THEREOF, AND USE THEREOF AS MEDICAMENTS BOEHRINGER INGELHEIM INT (DE) 2008-03-12 EP claimed