Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 9/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | NAMPT | P43490 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 6/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479306 | 1.00 | MAPT (0.46) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL479308 | 1.00 | MAPT (0.46) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2569854 | 0.92 | ALDH1A1 (0.44) | MAPTRXFP1NPC1RAB9AKMT2A | |
| SCHEMBL2569857 | 0.92 | ALDH1A1 (0.44) | MAPTRXFP1NPC1RAB9AKMT2A | |
| SCHEMBL479480 | 0.91 | RXFP1 (0.47) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL479481 | 0.91 | RXFP1 (0.47) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL479479 | 0.91 | RXFP1 (0.47) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2122106 | 0.91 | RXFP1 (0.47) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2122102 | 0.91 | RXFP1 (0.47) | MAPTRXFP1SMN1; SMN2GAANPC1 | |
| SCHEMBL2573269 | 0.90 | MAPT (0.51) | MAPTRXFP1SMN1; SMN2GAANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |