Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 5/20 | 0.40 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | ATP4A | P20648 | 2/20 | 0.33 |
| ▸ | ATP4B | P51164 | 2/20 | 0.33 |
| ▸ | RPS6KA5 | O75582 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4791598 | 0.94 | ALDH1A1 (0.37) | TLR7ALDH1A1MCL1MAOAMAOB | |
| SCHEMBL4867497 | 0.91 | TLR7 (0.47) | TLR7TLR8ALDH1A1ATP4AATP4B | |
| SCHEMBL4793345 | 0.88 | TLR7 (0.47) | TLR7TLR8 | |
| SCHEMBL4794543 | 0.81 | TLR8 (0.45) | TLR7TLR8MCL1 | |
| SCHEMBL4795552 | 0.81 | TLR7 (0.42) | TLR7TLR8ALDH1A1MCL1MAOA | |
| SCHEMBL4792168 | 0.81 | TLR7 (0.36) | TLR7TLR8ATP4AATP4B | |
| SCHEMBL4792812 | 0.80 | ALDH1A1 (0.52) | TLR7ALDH1A1CDK9DYRK1ADYRK2 | |
| SCHEMBL4792178 | 0.79 | TLR7 (0.45) | TLR7TLR8ADORA2AADORA1 | |
| SCHEMBL4794665 | 0.78 | TLR8 (0.59) | TLR7TLR8 | |
| SCHEMBL4790622 | 0.78 | TLR7 (0.54) | TLR7TLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1513524-A4 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES CO (US) | 2008-09-03 | — | — | EP | disclosed |
| EP-1513524-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M Innovative Properties Company (US) | 2005-03-16 | — | — | EP | disclosed |
| WO-2003103584-A2 | ETHER SUBSTITUTED IMIDAZOPYRIDINES | 3M INNOVATIVE PROPERTIES COMPANY (US) | 2003-12-18 | — | — | WO | disclosed |