Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 7/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4500713 | 1.00 | KCNH2 (0.51) | KCNH2 | |
| SCHEMBL4772967 | 0.89 | KCNH2 (0.48) | KCNH2 | |
| SCHEMBL4512253 | 0.85 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL4522089 | 0.79 | KCNH2 (0.81) | KCNH2 | |
| SCHEMBL5636821 | 0.77 | KCNH2 (0.57) | KCNH2 | |
| SCHEMBL4511568 | 0.76 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL14128010 | 0.75 | KCNH2 (0.49) | KCNH2 | |
| SCHEMBL633958 | 0.73 | KCNH2 (0.54) | KCNH2 | |
| SCHEMBL5905772 | 0.73 | CYP8B1 (0.49) | KCNH2 | |
| SCHEMBL2332033 | 0.72 | KCNH2 (0.41) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1891078-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | AstraZeneca AB (SE) | 2008-02-27 | — | — | EP | disclosed |
| WO-2006125974-A1 | AMINOPIPERIDINE QUINOLINES AND THEIR AZAISOSTERIC ANALOGUES WITH ANTIBACTERIAL ACTIVITY | ASTRAZENECA AB (SE) | 2006-11-30 | — | — | WO | disclosed |