Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 5/20 | 0.60 |
| ▸ | HTR2A | P28223 | 5/20 | 0.58 |
| ▸ | TAAR1 | Q96RJ0 | 4/20 | 0.58 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.48 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.48 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | F2 | P00734 | 1/20 | 0.44 |
| ▸ | HTR1B | P28222 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3290730 | 0.80 | HRH1 (0.68) | HRH1HTR2ATAAR1DPP4 | |
| SCHEMBL9768633 | 0.79 | TAAR1 (0.61) | HRH1HTR2ATAAR1CHRNB2CHRNA4 | |
| SCHEMBL7771656 | 0.78 | HRH1 (0.50) | HRH1HTR2ATAAR1DPP4F2 | |
| SCHEMBL8217290 | 0.78 | HRH1 (0.61) | HRH1HTR2ATAAR1DPP4F2 | |
| SCHEMBL27321444 | 0.77 | HRH1 (0.65) | HRH1HTR2ATAAR1DPP4 | |
| SCHEMBL2732016 | 0.77 | HRH1 (0.65) | HRH1HTR2ATAAR1DPP4 | |
| SCHEMBL844862 | 0.77 | HRH1 (0.65) | HRH1HTR2ATAAR1DPP4 | |
| Hydrochloric Acid SCHEMBL7159533 | 0.77 | HRH1 (0.48) | HRH1HTR2ATAAR1DPP4 | |
| SCHEMBL158098 | 0.75 | HRH1 (1.00) | HRH1HTR2ATAAR1CHRNB2CHRNA4 | |
| SCHEMBL149259 | 0.75 | HTR2A (1.00) | HRH1HTR2ATAAR1CHRNB2CHRNA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1909780-A2 | ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS | Sequella, Inc. (US) | 2008-04-16 | — | — | EP | disclosed |
| WO-2007005896-A2 | ANTI-TUBERCULAR DRUGS: COMPOSITIONS AND METHODS | SEQUELLA, INC. (US) | 2007-01-11 | — | — | WO | disclosed |