Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.50 |
| ▸ | SYK | P43405 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 4/20 | 0.47 |
| ▸ | CAMKK2 | Q96RR4 | 3/20 | 0.47 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.46 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.46 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.46 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.46 |
| ▸ | CAMK2D | Q13557 | 2/20 | 0.43 |
| ▸ | AXL | P30530 | 2/20 | 0.41 |
| ▸ | SGK1 | O00141 | 1/20 | 0.41 |
| ▸ | GSK3A | P49840 | 2/20 | 0.41 |
| ▸ | FLT1 | P17948 | 1/20 | 0.41 |
| ▸ | FLT4 | P35916 | 1/20 | 0.41 |
| ▸ | KDR | P35968 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1734253 | 0.81 | CSNK2A1 (0.54) | CSNK2A1SYKGSK3BCAMKK2MAPK8 | |
| SCHEMBL6016825 | 0.72 | SYK (0.65) | SYKGSK3BMAPK8CAMK2DAXL | |
| SCHEMBL13472148 | 0.70 | CSNK2A1 (0.73) | CSNK2A1GSK3BHDAC3HDAC1HDAC2 | |
| SCHEMBL27040648 | 0.69 | RHOA (0.60) | SYKHDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL29818028 | 0.68 | HDAC1 (0.60) | CSNK2A1SYKGSK3BCAMKK2MAPK8 | |
| SCHEMBL1735277 | 0.67 | CSNK2A1 (0.68) | CSNK2A1HDAC3HDAC1HDAC2HDAC6 | |
| SCHEMBL5495448 | 0.67 | RHOA (0.53) | CSNK2A1SYKHDAC3HDAC1HDAC2 | |
| Trifluoroacetic Acid SCHEMBL8085100 | 0.67 | SYK (0.71) | SYKGSK3BCAMKK2MAPK8PIK3CG | |
| SCHEMBL180770 | 0.67 | HDAC3 (0.46) | CSNK2A1SYKGSK3BCAMKK2MAPK8 | |
| SCHEMBL29817836 | 0.66 | HDAC6 (0.51) | CSNK2A1GSK3BCAMKK2MAPK8PIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007038669-A9 | DIARYLAMINE-CONTAINING COMPOUNDS AND COMPOSITIONS, AND THEIR USE AS MODULATORS OF C-KIT RECEPTORS | IRM LLC | 2008-05-29 | — | — | WO | disclosed |