Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CD | O00329 | 3/20 | 0.48 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.45 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.42 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.42 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.42 |
| ▸ | HPGDS | O60760 | 3/20 | 0.40 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.39 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.39 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.37 |
| ▸ | AHR | P35869 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.36 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.35 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7089562 | 0.80 | PIK3CD (0.58) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL3937493 | 0.79 | PIK3CD (0.50) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL3936500 | 0.73 | PIK3CD (0.54) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL10945814 | 0.72 | PIK3CD (0.75) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL2156317 | 0.72 | PIK3CD (0.64) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL27454514 | 0.70 | PIK3CD (0.57) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL20540332 | 0.70 | PIK3CD (0.64) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL23259083 | 0.69 | ASH1L (0.59) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL6322509 | 0.69 | ASH1L (0.59) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 | |
| SCHEMBL2193011 | 0.69 | PIK3CD (0.70) | PIK3CDASH1LPIK3CBCSNK2BCSNK2A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |