Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 9/20 | 0.45 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.41 |
| ▸ | PIM1 | P11309 | 2/20 | 0.41 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.41 |
| ▸ | GSK3B | P49841 | 2/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.38 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.38 |
| ▸ | TUBB | P07437 | 1/20 | 0.38 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.38 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.38 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.38 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.38 |
| ▸ | TUBB3 | Q13509 | 1/20 | 0.38 |
| ▸ | TUBB2A | Q13885 | 1/20 | 0.38 |
| ▸ | TUBB8 | Q3ZCM7 | 1/20 | 0.38 |
| ▸ | TUBA3E | Q6PEY2 | 1/20 | 0.38 |
| ▸ | TUBA1A | Q71U36 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3937422 | 0.95 | HPGDS (0.43) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL3933459 | 0.94 | HPGDS (0.48) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL4795668 | 0.90 | HPGDS (0.46) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL4796842 | 0.90 | HPGDS (0.46) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL4794843 | 0.88 | HPGDS (0.44) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL4154298 | 0.88 | HPGDS (0.46) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL3933604 | 0.87 | HPGDS (0.42) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL3931103 | 0.87 | PIP4K2A (0.52) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL3927726 | 0.85 | HPGDS (0.44) | HPGDSPIK3CDPIM1PIK3CBGSK3B | |
| SCHEMBL4913243 | 0.85 | ATR (0.42) | PIK3CDPIK3CBPIK3CAPIK3CG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |