Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | SENP1 | Q9P0U3 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 4/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479474 | 1.00 | RXFP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2119827 | 1.00 | RXFP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL479767 | 0.95 | AAK1 (0.40) | RXFP1SENP1RAB9AALDH1A1MAPK1 | |
| SCHEMBL479769 | 0.95 | AAK1 (0.40) | RXFP1SENP1RAB9AALDH1A1MAPK1 | |
| SCHEMBL2119984 | 0.95 | AAK1 (0.40) | RXFP1SENP1RAB9AALDH1A1MAPK1 | |
| SCHEMBL2572844 | 0.94 | RXFP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL480859 | 0.92 | SENP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL2570146 | 0.92 | SENP1 (0.43) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3151609 | 0.90 | SENP1 (0.46) | RXFP1SENP1SMN1; SMN2NPC1RAB9A | |
| SCHEMBL3151615 | 0.90 | SENP1 (0.46) | RXFP1SENP1SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |