Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGDS | O60760 | 8/20 | 0.52 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.46 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.45 |
| ▸ | JAK3 | P52333 | 1/20 | 0.45 |
| ▸ | MELK | Q14680 | 1/20 | 0.45 |
| ▸ | FTO | Q9C0B1 | 1/20 | 0.43 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.43 |
| ▸ | PIM1 | P11309 | 2/20 | 0.43 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.43 |
| ▸ | GSK3B | P49841 | 2/20 | 0.43 |
| ▸ | PIP4K2A | P48426 | 1/20 | 0.42 |
| ▸ | PIP4K2B | P78356 | 1/20 | 0.42 |
| ▸ | PIP4K2C | Q8TBX8 | 1/20 | 0.42 |
| ▸ | ASH1L | Q9NR48 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | BTK | Q06187 | 1/20 | 0.41 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4793555 | 0.82 | HPGDS (0.49) | HPGDSPIK3C3JAK3MELKFTO | |
| SCHEMBL3929164 | 0.82 | PIK3CD (0.58) | HPGDSPIK3C3JAK3MELKPIK3CD | |
| SCHEMBL4798306 | 0.81 | PIP4K2A (0.63) | HPGDSMAPK14FTOPIK3CDPIK3CB | |
| SCHEMBL4793945 | 0.81 | HPGDS (0.47) | HPGDSMAPK14PIK3C3JAK3MELK | |
| SCHEMBL4793977 | 0.81 | HPGDS (0.47) | HPGDSMAPK14PIK3C3JAK3MELK | |
| SCHEMBL3928845 | 0.80 | HPGDS (0.57) | HPGDSPIK3C3JAK3MELKPIK3CD | |
| SCHEMBL3929354 | 0.80 | HPGDS (0.52) | HPGDSPIK3C3JAK3MELKPIK3CD | |
| SCHEMBL4796087 | 0.80 | HPGDS (0.47) | HPGDSPIK3C3JAK3MELKPIK3CD | |
| SCHEMBL3930098 | 0.78 | HPGDS (0.55) | HPGDSPIK3C3JAK3MELKPIK3CD | |
| SCHEMBL4794592 | 0.78 | HPGDS (0.48) | HPGDSPIK3C3JAK3MELKFTO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080280891-A1 | Anti-cancer agents and uses thereof | LOCUS PHARMACEUTICALS, INC. (US) | 2008-11-13 | — | — | US | disclosed |
| WO-2008008059-A1 | ANTI-CANCER AGENTS ANS USES THEREOF | LOCUS PHARMACEUTICALS, INC. (US) | 2008-01-17 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080280891-A1 | Anti-cancer agents and uses thereof | NR2E3, RB1, CBR3 | HPGDS 2387/4885MAPK14 3831/4885PIK3C3 3695/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.