Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 11/20 | 0.39 |
| ▸ | TP53 | P04637 | 4/20 | 0.39 |
| ▸ | RAB9A | P51151 | 5/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | NAMPT | P43490 | 3/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2568481 | 1.00 | RXFP1 (0.44) | RXFP1MAPTTP53RAB9ANPC1 | |
| SCHEMBL2118006 | 1.00 | RXFP1 (0.44) | RXFP1MAPTTP53RAB9ANPC1 | |
| SCHEMBL2567564 | 0.93 | RXFP1 (0.43) | RXFP1MAPTTP53RAB9ANPC1 | |
| SCHEMBL479333 | 0.93 | RXFP1 (0.43) | RXFP1MAPTTP53RAB9ANPC1 | |
| SCHEMBL2119693 | 0.92 | KMT2A (0.40) | RXFP1MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL479766 | 0.92 | KMT2A (0.40) | RXFP1MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL2572117 | 0.92 | KMT2A (0.40) | RXFP1MAPTTP53POLBSMN1; SMN2 | |
| SCHEMBL2569840 | 0.90 | RXFP1 (0.45) | RXFP1MAPTTP53RAB9ANPC1 | |
| SCHEMBL480512 | 0.90 | RXFP1 (0.45) | RXFP1MAPTTP53RAB9ANPC1 | |
| SCHEMBL480580 | 0.87 | RXFP1 (0.48) | RXFP1MAPTTP53RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |