Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 5/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LSS | P48449 | 1/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2119693 | 1.00 | KMT2A (0.40) | KMT2ACTDSP1CASP1ROCK2CYP3A4 | |
| SCHEMBL2572117 | 1.00 | KMT2A (0.40) | KMT2ACTDSP1CASP1ROCK2CYP3A4 | |
| SCHEMBL479842 | 0.92 | CASP1 (0.41) | KMT2ACTDSP1CASP1ROCK2CYP3A4 | |
| SCHEMBL2569108 | 0.92 | CASP1 (0.41) | KMT2ACTDSP1CASP1ROCK2CYP3A4 | |
| SCHEMBL2568481 | 0.92 | RXFP1 (0.44) | KMT2AMAPTALDH1A1RXFP1POLB | |
| SCHEMBL2118006 | 0.92 | RXFP1 (0.44) | KMT2AMAPTALDH1A1RXFP1POLB | |
| SCHEMBL479555 | 0.92 | RXFP1 (0.44) | KMT2AMAPTALDH1A1RXFP1POLB | |
| SCHEMBL2571689 | 0.88 | KMT2A (0.42) | KMT2ACTDSP1CASP1ROCK2CYP3A4 | |
| SCHEMBL2119775 | 0.88 | KMT2A (0.42) | KMT2ACTDSP1CASP1ROCK2CYP3A4 | |
| SCHEMBL479403 | 0.87 | KMT2A (0.44) | KMT2ACTDSP1CASP1MAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |