Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.65 |
| ▸ | HTR2C | P28335 | 18/20 | 0.65 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4780050 | 0.90 | HTR2A (0.63) | HTR2AHTR2C | |
| SCHEMBL14259726 | 0.85 | HTR2A (0.62) | HTR2AHTR2CGAA | |
| SCHEMBL29573349 | 0.83 | HTR2A (0.78) | HTR2AHTR2CGAA | |
| SCHEMBL5052914 | 0.83 | HTR2A (0.78) | HTR2AHTR2CGAA | |
| SCHEMBL4727433 | 0.83 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL4728076 | 0.82 | HTR2A (0.70) | HTR2AHTR2C | |
| SCHEMBL4726660 | 0.82 | HTR2A (0.65) | HTR2AHTR2C | |
| SCHEMBL4781004 | 0.81 | HTR2A (0.64) | HTR2AHTR2C | |
| SCHEMBL12391709 | 0.81 | HTR2A (0.78) | HTR2AHTR2CGAA | |
| SCHEMBL4725894 | 0.81 | HTR2A (0.59) | HTR2AHTR2CGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |