Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 18/20 | 0.59 |
| ▸ | HTR2C | P28335 | 18/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4727771 | 0.91 | HTR2A (0.57) | HTR2AHTR2C | |
| SCHEMBL14259726 | 0.89 | HTR2A (0.62) | HTR2AHTR2CGAA | |
| SCHEMBL4780191 | 0.85 | HTR2A (0.62) | HTR2AHTR2C | |
| SCHEMBL4725737 | 0.84 | HTR2A (0.59) | HTR2AHTR2C | |
| SCHEMBL4727184 | 0.84 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL4795576 | 0.81 | HTR2A (0.65) | HTR2AHTR2CGAA | |
| SCHEMBL4780226 | 0.79 | HTR2A (0.60) | HTR2AHTR2C | |
| SCHEMBL4780197 | 0.79 | HTR2A (0.42) | HTR2AHTR2C | |
| SCHEMBL12391709 | 0.77 | HTR2A (0.78) | HTR2AHTR2CGAA | |
| SCHEMBL4881352 | 0.76 | HTR2A (0.39) | HTR2AHTR2CTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008027483-A1 | BENZOFURAN DERIVATIVES AS MODULATORS OF THE 5-HT2A RECEPTOR | ARENA PHARMACEUTICALS, INC. (US) | 2008-03-06 | — | — | WO | disclosed |