Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 2/20 | 0.40 |
| ▸ | BRD2 | P25440 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.39 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.38 |
| ▸ | RET | P07949 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | FLT4 | P35916 | 1/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | FLT3 | P36888 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2121532 | 0.90 | KMT2A (0.40) | BRD4BRD2KMT2ACTDSP1POLB | |
| SCHEMBL480655 | 0.90 | KMT2A (0.40) | BRD4BRD2KMT2ACTDSP1POLB | |
| SCHEMBL479436 | 0.89 | MAPT (0.40) | KMT2ACTDSP1POLBTP53THRB | |
| SCHEMBL479448 | 0.89 | KMT2A (0.39) | KMT2ACTDSP1POLBTP53THRB | |
| SCHEMBL479616 | 0.89 | NOTUM (0.40) | KMT2ACTDSP1POLBTP53THRB | |
| SCHEMBL480718 | 0.88 | KMT2A (0.38) | BRD4BRD2KMT2ACTDSP1POLB | |
| SCHEMBL480387 | 0.86 | CASP3 (0.39) | KMT2ACTDSP1POLBTP53THRB | |
| SCHEMBL2568537 | 0.86 | KMT2A (0.43) | KMT2ACTDSP1POLBTP53THRB | |
| SCHEMBL479891 | 0.85 | HTT (0.41) | BRD4BRD2KMT2ACTDSP1POLB | |
| SCHEMBL19133985 | 0.85 | HTT (0.41) | BRD4BRD2KMT2ACTDSP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |