Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4796274 | 1.00 | KDM4E (0.31) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL2433831 | 0.91 | POLB (0.32) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL2433828 | 0.91 | POLB (0.32) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL2434814 | 0.91 | KDM4E (0.32) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL2434817 | 0.91 | KDM4E (0.32) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL2434282 | 0.88 | — | — | |
| SCHEMBL2434279 | 0.88 | — | — | |
| SCHEMBL2427752 | 0.87 | KDM4E (0.33) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL2427754 | 0.87 | KDM4E (0.33) | KDM4EHTTATMALDH1A1TP53 | |
| SCHEMBL4344584 | 0.82 | ALDH1A1 (0.41) | KDM4EHTTATMALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008017688-A1 | 2-CARBOXY THIOPHENE DERIVATIVES AS ANTI-VIRAL AGENTS | SMITHKLINE BEECHAM CORPORATION (US) | 2008-02-14 | — | — | WO | disclosed |