Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 9/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | EBP | Q15125 | 5/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | UBE2M | P61081 | 1/20 | 0.42 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3022931 | 0.88 | CCR2 (0.50) | CCR2CYP3A4ALDH1A1EBPHTT | |
| SCHEMBL3042038 | 0.82 | CCR2 (0.55) | CCR2EBPKCNH2 | |
| SCHEMBL3023614 | 0.79 | CCR2 (0.51) | CCR2EBP | |
| SCHEMBL3023281 | 0.79 | CCR2 (0.56) | CCR2EBP | |
| SCHEMBL3042043 | 0.76 | CCR2 (0.49) | CCR2CYP3A4EBPUBE2MDCUN1D1 | |
| SCHEMBL3040350 | 0.76 | HRH3 (0.50) | CCR2CYP3A4EBPUBE2MDCUN1D1 | |
| SCHEMBL3036595 | 0.76 | CCR2 (0.50) | CCR2EBP | |
| SCHEMBL3039259 | 0.75 | CCR2 (0.48) | CCR2CYP3A4EBPKCNH2 | |
| SCHEMBL3041700 | 0.75 | CCR2 (0.47) | CCR2CYP3A4ALDH1A1EBPKCNH2 | |
| SCHEMBL13789280 | 0.75 | CCR2 (0.70) | CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008045564-A2 | CARBOXAMIDE COMPOUNDS AND THEIR USE AS ANTAGONISTS OF THE CHEMOKINE CCR2 RECEPTOR | EPIX DELAWARE, INC. (US) | 2008-04-17 | — | — | WO | claimed |