Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKB | Q96GD4 | 2/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CSF1R | P07333 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | FLT3 | P36888 | 2/20 | 0.33 |
| ▸ | NTRK3 | Q16288 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.33 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.33 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479632 | 1.00 | AURKB (0.37) | AURKBRXFP1ALDH1A1KMT2ACSF1R | |
| SCHEMBL480621 | 0.85 | ALDH1A1 (0.43) | AURKBRXFP1ALDH1A1KMT2ACSF1R | |
| SCHEMBL3153364 | 0.85 | ALDH1A1 (0.43) | AURKBRXFP1ALDH1A1KMT2ACSF1R | |
| SCHEMBL2569434 | 0.82 | RXFP1 (0.39) | RXFP1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL2569433 | 0.82 | RXFP1 (0.39) | RXFP1ALDH1A1KMT2ASMN1; SMN2NPC1 | |
| SCHEMBL479789 | 0.79 | ALDH1A1 (0.46) | RXFP1ALDH1A1KMT2ACSF1RSMN1; SMN2 | |
| SCHEMBL479791 | 0.79 | ALDH1A1 (0.46) | RXFP1ALDH1A1KMT2ACSF1RSMN1; SMN2 | |
| SCHEMBL2567922 | 0.79 | ALDH1A1 (0.46) | RXFP1ALDH1A1KMT2ACSF1RSMN1; SMN2 | |
| SCHEMBL479417 | 0.78 | AURKA (0.41) | AURKBALDH1A1KMT2ACSF1RFLT3 | |
| SCHEMBL2563861 | 0.78 | AURKA (0.41) | AURKBALDH1A1KMT2ACSF1RFLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |