Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR4 | O00206 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9758005 | 0.82 | TLR4 (0.40) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL3171794 | 0.78 | TLR4 (0.38) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL4870636 | 0.78 | MAPT (0.33) | ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL8052103 | 0.76 | FFAR3 (0.43) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL9758567 | 0.76 | CYP4F2 (0.44) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL5069946 | 0.75 | TLR4 (0.42) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL9758596 | 0.75 | CYP4F2 (0.47) | TLR4KMT2ACYP2C9 | |
| SCHEMBL9757879 | 0.75 | CYP4F2 (0.38) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL9758906 | 0.75 | TLR4 (0.36) | TLR4ALDH1A1MAPTLMNAKMT2A | |
| SCHEMBL14138017 | 0.75 | TLR4 (0.39) | TLR4ALDH1A1MAPTLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1955991-A2 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | Air Products and Chemicals, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| EP-1955991-A2 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | Air Products and Chemicals, Inc. (US) | 2008-08-13 | — | — | EP | disclosed |
| US-20080188689-A1 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | VERSUM MATERIALS US, LLC | 2008-08-07 | — | — | US | disclosed |
| US-20080188689-A1 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | VERSUM MATERIALS US, LLC | 2008-08-07 | — | — | US | disclosed |
| US-20080188689-A1 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | VERSUM MATERIALS US, LLC | 2008-08-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080188689-A1 | Preparation of organic compounds bearing a trifluoromethyl group on a quaternary carbon | AFF4, RFC4, SF3B3 | TLR4 2618/4885ALDH1A1 2902/4885MAPT 3415/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.