SCHEMBL5069946

SCHEMBL5069946

CCCC1CCC(C2CCC(Cl)(C(=O)O)CC2)CC1

nearest known ligand 0.42

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TLR4 O00206 2/20 0.42
CYP2C9 P11712 1/20 0.35
MAPT P10636 2/20 0.33
ALDH1A1 P00352 2/20 0.33
LMNA P02545 1/20 0.33
SLC1A2 P43004 1/20 0.30
KMT2A Q03164 1/20 0.30
ARG1 P05089 1/20 0.30
ARG2 P78540 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7876219 0.90 ARG1 (0.36) TLR4CYP2C9MAPTALDH1A1LMNA
SCHEMBL10926813 0.86 POLB (0.32)
SCHEMBL8052103 0.81 FFAR3 (0.43) TLR4CYP2C9MAPTALDH1A1LMNA
SCHEMBL1508100 0.79 MAPT (0.44) TLR4CYP2C9MAPTALDH1A1LMNA
Acetic Acid SCHEMBL8734367 0.79 TLR4 (0.46) TLR4CYP2C9MAPTALDH1A1LMNA
SCHEMBL2576207 0.78 TP53 (0.40) CYP2C9MAPTKMT2A
SCHEMBL10902327 0.78 MAPT (0.43) TLR4CYP2C9MAPTLMNAKMT2A
SCHEMBL14097861 0.78 TLR4 (0.37) TLR4CYP2C9MAPTALDH1A1LMNA
SCHEMBL2148374 0.77 CYP1A2 (0.40) TLR4CYP2C9MAPTALDH1A1LMNA
SCHEMBL10450411 0.77 TP53 (0.43) CYP2C9MAPTALDH1A1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2008091090-A1 NOVEL LIQUID CRYSTAL COMPOUND CONTAINING SULFONE GROUP, LIQUID CRYSTAL COMPOSITION COMPRISING THE SAME, AND OPTICAL FILM USING THE SAME LIQUID CRYSTAL COMPOSITION LG CHEM, LTD. (KR) 2008-07-31 WO disclosed
US-4853151-A LIQUID CRYSTALS MERCK PATENT GESELLSCHAFT MIT BESCHRANKFTER HAFTUNG (DE) 1989-08-01 US disclosed
US-4603018-A NEGATIVE DIELECTRIC ANISOTROPIC LIQUID CRYSTALS CHISSO CORPORATION (JP) 1986-07-29 US disclosed
EP-0106588-B1 2-CYANO-4-HALOGENOPHENYL ESTERS Chisso Corporation (JP) 1986-04-30 EP disclosed
EP-0106588-A1 2-Cyano-4-halogenophenyl esters Chisso Corporation (JP) 1984-04-25 EP disclosed