Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | MCHR1 | Q99705 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.38 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479735 | 1.00 | RXFP1 (0.44) | RXFP1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL479733 | 1.00 | RXFP1 (0.44) | RXFP1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL2571276 | 0.95 | RXFP1 (0.42) | RXFP1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL2571272 | 0.95 | RXFP1 (0.42) | RXFP1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL2571487 | 0.94 | MCHR1 (0.41) | SMN1; SMN2MCHR1MEN1KMT2AHDAC1 | |
| SCHEMBL2571485 | 0.94 | MCHR1 (0.41) | SMN1; SMN2MCHR1MEN1KMT2AHDAC1 | |
| SCHEMBL3714775 | 0.94 | MCHR1 (0.41) | SMN1; SMN2MCHR1MEN1KMT2AHDAC1 | |
| SCHEMBL479701 | 0.93 | RXFP1 (0.45) | RXFP1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL479699 | 0.93 | RXFP1 (0.45) | RXFP1SMN1; SMN2NPC1RAB9AGAA | |
| SCHEMBL479697 | 0.93 | RXFP1 (0.45) | RXFP1SMN1; SMN2NPC1RAB9AGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |