Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | LTA4H | P09960 | 3/20 | 0.39 |
| ▸ | ACHE | P22303 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2571485 | 1.00 | MCHR1 (0.41) | MCHR1HDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL2571487 | 1.00 | MCHR1 (0.41) | MCHR1HDAC1HDAC6KDM4EALDH1A1 | |
| SCHEMBL2570281 | 0.95 | ACHE (0.41) | MCHR1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL2570287 | 0.95 | ACHE (0.41) | MCHR1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL30708647 | 0.95 | ACHE (0.41) | MCHR1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL479732 | 0.94 | RXFP1 (0.44) | MCHR1HDAC1HDAC6ALDH1A1KMT2A | |
| SCHEMBL479735 | 0.94 | RXFP1 (0.44) | MCHR1HDAC1HDAC6ALDH1A1KMT2A | |
| SCHEMBL479733 | 0.94 | RXFP1 (0.44) | MCHR1HDAC1HDAC6ALDH1A1KMT2A | |
| SCHEMBL3148338 | 0.92 | KDM4E (0.41) | MCHR1KDM4EALDH1A1KMT2AMEN1 | |
| SCHEMBL3158720 | 0.92 | LTA4H (0.41) | MCHR1KDM4EALDH1A1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |