SCHEMBL4797443

SCHEMBL4797443

c1ccc(Nc2ccc(Nc3cccc4ccccc34)cc2)cc1

nearest known ligand 0.92

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 7/20 0.92
HSD17B10 Q99714 4/20 0.92
HPGD P15428 3/20 0.92
CYP3A4 P08684 3/20 0.92
ALOX15 P16050 2/20 0.92
TSHR P16473 2/20 0.92
ATM Q13315 2/20 0.92
CDC25B P30305 2/20 0.92
TP53 P04637 1/20 0.92
MAPT P10636 5/20 0.72
MEN1 O00255 5/20 0.72
KMT2A Q03164 5/20 0.72
KDM4E B2RXH2 3/20 0.72
GAA P10253 3/20 0.72
TDP1 Q9NUW8 2/20 0.72
RECQL P46063 2/20 0.72
GLA P06280 1/20 0.72
RAB9A P51151 2/20 0.66
FADS1 O60427 1/20 0.62
ALOX12 P18054 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29609502 1.00 ALDH1A1 (0.92) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
Diphenylamine SCHEMBL1072941 0.98 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL29350230 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL19796 0.96 ALDH1A1 (1.00) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL4884667 0.94 ALDH1A1 (0.81) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL9486043 0.94 ALDH1A1 (0.81) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
Diphenylamine SCHEMBL8023920 0.94 HSD17B10 (0.88) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
Ammonia Solution, Strong SCHEMBL20918916 0.94 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
Hydrochloric Acid SCHEMBL7408656 0.94 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDCYP3A4ALOX15
SCHEMBL28286951 0.94 ALDH1A1 (0.96) ALDH1A1HSD17B10HPGDCYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143433-B Low-dielectric-constant adhesive and preparation method thereof 中瀚新材料科技有限公司 2022-05-24 CN disclosed
US-10892414-B2 Process for making electronic device MERCK PATENT GMBH (DE) 2021-01-12 US disclosed
US-20200066990-A1 PREPARATION PROCESS FOR AN ELECTRONIC DEVICE MERCK PATENT GMBH (DE) 2020-02-27 US disclosed
CN-100528831-C Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2009-08-19 CN disclosed
US-20080241591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND PHENYLENEDIAMINE DERIVATIVE IDEMITSU KOSAN CO., LTD. (JP) 2008-10-02 US disclosed
US-7399537-B2 Organic electroluminescence device and phenylenediamine derivative IDEMITSU KOSAN CO., LTD. (JP) 2008-07-15 US disclosed
CN-101096344-A Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2008-01-02 CN disclosed
US-20060082294-A1 Organic electroluminescence device and phenylenediamine derivative IDEMITSU KOSAN CO., LTD. (JP) 2006-04-20 US disclosed
CN-1733700-A Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2006-02-15 CN disclosed
CN-1213127-C Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2005-08-03 CN disclosed
US-20030143430-A1 Organic electroluminescence device and phenylenediamine derivative IDEMITSU KOSAN CO., LTD. (JP) 2003-07-31 US disclosed
US-6541129-B1 Having a long life time that can decrease the driving voltage; using a phenylenediamine material having a small ionization potential and exhibiting a large hole mobility IDEMITSU KOSAN CO., LTD. (JP) 2003-04-01 US disclosed
CN-1277626-A Organic electroluminescent device and phenylenediamine derivative IDEMITSU KOSAN CO (JP) 2000-12-20 CN disclosed
EP-1029909-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND PHENYLENEDIAMINE DERIVATIVE Idemitsu Kosan Co., Ltd. (JP) 2000-08-23 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080241591-A1 ORGANIC ELECTROLUMINESCENCE DEVICE AND PHENYLENEDIAMINE DERIVATIVE MAL2, L1CAM, EPCAM ALDH1A1 734/4885HSD17B10 1666/4885HPGD 2766/4885
US-20030143430-A1 Organic electroluminescence device and phenylenediamine derivative MAL2, SLC7A5, OCIAD2 ALDH1A1 755/4885HSD17B10 1312/4885HPGD 2519/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.