Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 18/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 18/20 | 0.57 |
| ▸ | RECQL | P46063 | 15/20 | 0.57 |
| ▸ | MAPT | P10636 | 13/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 11/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 10/20 | 0.57 |
| ▸ | MITF | O75030 | 9/20 | 0.57 |
| ▸ | GFER | P55789 | 3/20 | 0.57 |
| ▸ | BLM | P54132 | 6/20 | 0.57 |
| ▸ | USP2 | O75604 | 2/20 | 0.57 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.57 |
| ▸ | KDM4A | O75164 | 1/20 | 0.57 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.57 |
| ▸ | POLB | P06746 | 11/20 | 0.56 |
| ▸ | L3MBTL1 | Q9Y468 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | HTT | P42858 | 5/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.56 |
| ▸ | NSD2 | O96028 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3765388 | 0.84 | MEN1 (0.67) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL3765392 | 0.84 | MEN1 (0.67) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL13848491 | 0.72 | KMT2A (1.00) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL26458992 | 0.72 | MEN1 (1.00) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL14712893 | 0.72 | MEN1 (0.74) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL15347317 | 0.68 | MAPT (0.65) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL15347315 | 0.68 | MAPT (0.65) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL12218053 | 0.68 | MAPT (0.65) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL14712984 | 0.67 | MEN1 (0.80) | MEN1KMT2ARECQLMAPTNPSR1 | |
| SCHEMBL3471120 | 0.67 | MEN1 (0.80) | MEN1KMT2ARECQLMAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | claimed |
| US-7344850-B2 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | PRINCETON UNIVERSITY (US) | 2008-03-18 | — | — | US | disclosed |
| US-20050142629-A1 | Identification of active-site inhibitors of glycosyltransferases using a generalizable high-throughput screen | NATIONAL INSTITUTES OF HEALTH | 2005-06-30 | — | — | US | disclosed |