Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 2/20 | 0.60 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | CHRNA7 | P36544 | 4/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.45 |
| ▸ | HTR3B | O95264 | 1/20 | 0.45 |
| ▸ | HTR3A | P46098 | 1/20 | 0.45 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.45 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.45 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.43 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.41 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | SCN1A | P35498 | 1/20 | 0.40 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.40 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL51072 | 0.88 | TSHR (0.70) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL4797945 | 0.87 | TSHR (0.60) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL7190461 | 0.84 | GAA (0.57) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL9065750 | 0.81 | TSHR (0.65) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL7857242 | 0.80 | TSHR (0.67) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL27490246 | 0.79 | TSHR (0.57) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL4804356 | 0.79 | TSHR (0.57) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL243559 | 0.79 | TSHR (0.70) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL294975 | 0.79 | TSHR (0.70) | TSHRGAAKMT2AMEN1CHRNA7 | |
| SCHEMBL11282679 | 0.79 | TSHR (0.62) | TSHRGAAKMT2AMEN1CHRNA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7402639-B2 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | CIBA SPECIALTY CHEMICALS CORP. (US) | 2008-07-22 | — | — | US | disclosed |
| EP-1873199-A1 | In-can stabilizers | Ciba Specialty Chemicals Holding Inc. (CH) | 2008-01-02 | — | — | EP | disclosed |
| US-20070225397-A1 | In-Can Stabilizers | CIBA SPECIALTY CHEMICALS CORP. | 2007-09-27 | — | — | US | disclosed |
| US-6927295-B2 | A polymerization catalyst for free radical polymerization of ethylenically unsaturated monomers | CIBA SPECIALTY CHEMICALS CORP. (US) | 2005-08-09 | — | — | US | disclosed |
| US-20050131177-A1 | 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (SE) | 2005-06-16 | — | — | US | disclosed |
| US-6683142-B2 | PROVIDE POLYMERIC RESIN PRODUCTS HAVING LOW POLYDISPERSITY. | CIBA SPECIALTY CHEMICALS CORPORATION | 2004-01-27 | — | — | US | disclosed |
| US-20030220423-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (CH) | 2003-11-27 | — | — | US | disclosed |
| US-20020107397-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | KRAMER ANDREAS (CH) | 2002-08-08 | — | — | US | disclosed |
| US-6353107-B1 | FREE RADICAL CATALYSTS FOR ADDITION POLYMERIZATION; NARROW MOLECULAR WEIGHT DISTRIBUTION; HIGH PURITY AND COLORLESS | CIBA SPECIALTY CHEMICALS CORPORATION | 2002-03-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050131177-A1 | 1-Alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | PYM1, PTGER1, CBR1 | TSHR 4811/4885GAA 3127/4885KMT2A 3106/4885 |
| US-20020107397-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | CBR1, PYM1, ELOC | TSHR 4803/4885GAA 2233/4885KMT2A 3370/4885 |
| US-20030220423-A1 | 1-alkoxy-polyalkyl-piperidine derivatives and their use as polymerization regulators | PYM1, ELOC, CBR1 | TSHR 4813/4885GAA 2416/4885KMT2A 3222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.