Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | MEN1 | O00255 | 4/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | CASP3 | P42574 | 1/20 | 0.50 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.50 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.50 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | NAMPT | P43490 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | CETP | P11597 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | TDO2 | P48775 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479806 | 1.00 | BACE1 (0.51) | BACE1MAPTMEN1KMT2ACASP3 | |
| SCHEMBL479808 | 1.00 | BACE1 (0.51) | BACE1MAPTMEN1KMT2ACASP3 | |
| SCHEMBL481167 | 0.93 | RXFP1 (0.51) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL481166 | 0.93 | RXFP1 (0.51) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL3159875 | 0.92 | RXFP1 (0.51) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL2569219 | 0.92 | RXFP1 (0.51) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL2572324 | 0.92 | RXFP1 (0.51) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL2572320 | 0.92 | RXFP1 (0.51) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL6771491 | 0.91 | RXFP1 (0.50) | MAPTMEN1KMT2ARXFP1SMN1; SMN2 | |
| SCHEMBL20807625 | 0.91 | RXFP1 (0.52) | BACE1MAPTMEN1KMT2ARXFP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |