Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | AURKB | Q96GD4 | 3/20 | 0.35 |
| ▸ | FLT3 | P36888 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.35 |
| ▸ | DRD4 | P21917 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | HTR2C | P28335 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.35 |
| ▸ | HRH1 | P35367 | 1/20 | 0.35 |
| ▸ | DRD3 | P35462 | 1/20 | 0.35 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL479339 | 0.88 | MAPT (0.36) | RAB9ANPC1SMN1; SMN2AURKBFLT3 | |
| SCHEMBL479888 | 0.88 | POLB (0.36) | RAB9APOLBNPC1SMN1; SMN2AURKB | |
| SCHEMBL2119702 | 0.85 | POLB (0.39) | RAB9APOLBNPC1SMN1; SMN2AURKB | |
| SCHEMBL2571394 | 0.85 | POLB (0.39) | RAB9APOLBNPC1SMN1; SMN2AURKB | |
| SCHEMBL479774 | 0.85 | CHEK1 (0.36) | RAB9AAURKBFLT3LMNACYP1A2 | |
| SCHEMBL3721673 | 0.84 | AURKA (0.37) | RAB9APOLBAURKBFLT3LMNA | |
| SCHEMBL3721672 | 0.84 | AURKA (0.37) | RAB9APOLBAURKBFLT3LMNA | |
| SCHEMBL479844 | 0.83 | PSEN1 (0.39) | RAB9APOLBAURKBFLT3LMNA | |
| SCHEMBL479685 | 0.81 | CHEK1 (0.37) | RAB9AAURKBFLT3LMNACYP1A2 | |
| SCHEMBL479847 | 0.79 | PDPK1 (0.39) | POLBAURKBFLT3LMNABLM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2411034-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | Life & Brain GmbH (DE) | 2012-02-01 | — | — | EP | disclosed |
| WO-2010108665-A1 | PROMOTION OF NEURONAL INTEGRATION IN NEURAL STEM CELL GRAFTS | LIFE & BRAIN GMBH (DE) | 2010-09-30 | — | — | WO | disclosed |