SCHEMBL4798978

SCHEMBL4798978

CCCCCc1ccc(CCC2CCC([C@H]3CC[C@H](CCC)CC3)CC2)cc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SPHK1 Q9NYA1 8/20 0.45
ESR1 P03372 2/20 0.44
ADRA2A P08913 2/20 0.44
ADORA3 P0DMS8 2/20 0.44
TACR2 P21452 2/20 0.44
SLC6A2 P23975 2/20 0.44
SLC6A4 P31645 2/20 0.44
SLC6A3 Q01959 2/20 0.44
KDM4E B2RXH2 1/20 0.44
ALDH1A1 P00352 1/20 0.44
LMNA P02545 1/20 0.44
SHBG P04278 1/20 0.44
TP53 P04637 1/20 0.44
CYP3A4 P08684 1/20 0.44
HSPD1 P10809 1/20 0.44
ADRB3 P13945 1/20 0.44
HTR2C P28335 1/20 0.44
HSPE1 P61604 1/20 0.44
HIF1A Q16665 1/20 0.44
TST Q16762 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4798987 1.00 SPHK1 (0.45) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL4799001 1.00 SPHK1 (0.45) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL10715828 0.98 SPHK1 (0.48) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL10717129 0.98 SPHK1 (0.48) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL8433282 0.95 MAOA (0.43) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL7906147 0.95 MAOA (0.43) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL11069225 0.95 SPHK1 (0.49) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL11069222 0.95 SPHK1 (0.49) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL10718077 0.93 SPHK1 (0.45) SPHK1ESR1ADRA2AADORA3TACR2
SCHEMBL10718234 0.93 SPHK1 (0.45) SPHK1ESR1ADRA2AADORA3TACR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 46 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7445818-B2 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2008-11-04 US disclosed
US-20070275182-A1 Matrix liquid crystal display WEBER GEORG 2007-11-29 US disclosed
US-7186447-B2 Two plane parallel support plates with frame form cell, with integrated non-linear elements for switching individual picture elements on support plates, and nematic liquid crystal mixture is present in cell, having positive dielectric anisotropy and high resistivity MERCK PATENT GMBH (DE) 2007-03-06 US disclosed
US-20050196551-A1 Matrix liquid crystal display WEBER GEORG (DE) 2005-09-08 US disclosed
US-6905740-B2 The invention relates to a matrix liquid crystal display containing integrated non-linear elements and a liquid crystal mixture which has a particularly high resistivity. MERCK PATENT GMBH (DE) 2005-06-14 US disclosed
US-20030207046-A1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-11-06 US disclosed
US-6562419-B1 Matrix liquid crystal display MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2003-05-13 US disclosed
US-6210760-B1 SHORT SWITCHING TIMES AND GRADIENTS AND ANGULAR DEPENDENCIES MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 2001-04-03 US disclosed
US-6004479-A FLUOROETHERS FOR LIQUID CRYSTAL DISPLAYS AND DIELECTRICS MERCK KGAA (DE) 1999-12-21 US disclosed
EP-0394417-B2 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 1999-08-04 EP disclosed
EP-0365962-A1 Matrix-type liquid-crystal display MERCK PATENT GmbH (DE) 1990-05-02 EP disclosed
EP-0360851-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK PATENT GmbH (DE) 1990-04-04 EP disclosed
EP-0354940-A1 IMPROVED LIQUID CRYSTAL MIXTURE MERCK PATENT GmbH (DE) 1990-02-21 EP disclosed
EP-0338059-A1 IMPROVED LIQUID CRYSTAL MIXTURE CASIO COMPUTER COMPANY LIMITED (JP) 1989-10-25 EP disclosed
WO-1989008691-A1 SUPERTWIST LIQUID CRYSTAL DISPLAY MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-09-21 WO disclosed
EP-0332005-A1 Supertwist liquid-crystal display MERCK PATENT GmbH (DE) 1989-09-13 EP disclosed
WO-1989006677-A1 IMPROVED LIQUID CRYSTAL MIXTURE MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1989-07-27 WO disclosed
WO-1989003867-A1 IMPROVED LIQUID CRYSTAL MIXTURE CASIO COMPUTER COMPANY LIMITED (JP) 1989-05-05 WO disclosed
EP-0302916-A1 ELECTRO-OPTICAL DISPLAY ELEMENT. MERCK PATENT GMBH (DE) 1989-02-15 EP disclosed
WO-1988006178-A1 ELECTRO-OPTICAL DISPLAY ELEMENT MERCK Patent Gesellschaft mit beschränkter Haftung (DE) 1988-08-25 WO disclosed