Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 8/20 | 0.40 |
| ▸ | MAOA | P21397 | 7/20 | 0.40 |
| ▸ | KDM1A | O60341 | 5/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.40 |
| ▸ | CYP2B6 | P20813 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.40 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2103232 | 0.97 | — | — | |
| SCHEMBL1779485 | 0.97 | — | — | |
| SCHEMBL303054 | 0.97 | — | — | |
| SCHEMBL6519587 | 0.94 | TSHR (0.42) | TSHRGAAMAPTMAOBMAOA | |
| SCHEMBL27994625 | 0.94 | — | — | |
| SCHEMBL6468322 | 0.87 | TSHR (0.37) | TSHRGAAMAPTMAOBMAOA | |
| SCHEMBL4297438 | 0.78 | SLC18A3 (0.40) | GAAMAPTMAOBMAOAKDM1A | |
| SCHEMBL6523128 | 0.78 | TSHR (0.34) | TSHRGAAMAPTMAOBMAOA | |
| SCHEMBL779515 | 0.76 | SLC18A3 (0.43) | GAAMAPTCYP2C19CYP2D6SLC18A3 | |
| SCHEMBL1929909 | 0.74 | SLC18A3 (0.41) | TSHRGAAMAOBMAOAKDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1943261-A2 | DRUG-ELUTING STENTS COATED WITH NON-NUCLEOTIDE P2Y12 RECEPTOR ANTAGONIST COMPOUND | Inspire Pharmaceuticals, Inc. (US) | 2008-07-16 | — | — | EP | disclosed |
| WO-2007056217-A2 | DRUG-ELUTING STENTS COATED WITH NON-NUCLEOTIDE P2Y12 RECEPTOR ANTAGONIST COMPOUND | INSPIRE PHARMACEUTICALS, INC. (US) | 2007-05-18 | — | — | WO | disclosed |