Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.50 |
| ▸ | PLA2G6 | O60733 | 4/20 | 0.49 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.49 |
| ▸ | FAAH | O00519 | 1/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | TRPC5 | Q9UL62 | 1/20 | 0.49 |
| ▸ | TRPC6 | Q9Y210 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15874844 | 1.00 | IDO1 (0.50) | IDO1PLA2G6MAPTMAPK1ALDH1A1 | |
| SCHEMBL4802338 | 0.95 | IDO1 (0.51) | IDO1PLA2G6MAPTMAPK1ALDH1A1 | |
| SCHEMBL9328857 | 0.81 | CYP11B1 (0.37) | PLA2G6MAPTMAPK1ALDH1A1HPGD | |
| SCHEMBL15658910 | 0.81 | MAPT (0.36) | IDO1PLA2G6MAPTMAPK1ALDH1A1 | |
| SCHEMBL19993851 | 0.81 | NPSR1 (0.40) | IDO1PLA2G6MAPTMAPK1ALDH1A1 | |
| SCHEMBL13997857 | 0.80 | CYP1B1 (0.42) | MAPTMAPK1ALDH1A1HPGDLMNA | |
| SCHEMBL3250204 | 0.78 | IDO1 (0.41) | IDO1PLA2G6MAPTMAPK1ALDH1A1 | |
| SCHEMBL19993854 | 0.77 | SMN1; SMN2 (0.40) | MAPTBLMNPC1LMNARAB9A | |
| SCHEMBL19993899 | 0.77 | HCRTR1 (0.40) | IDO1MAPTMAPK1ALDH1A1NPSR1 | |
| SCHEMBL21722167 | 0.77 | GAA (0.43) | MAPTMAPK1ALDH1A1HPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111233599-B | Aromatic ring ortho-iodoalkanone and synthetic method and application thereof | 兰州大学 | 2021-07-20 | — | — | CN | disclosed |
| CN-109232149-B | Synthetic method of alpha-fluoro-alpha-substituted ketone with fluorine-containing quaternary carbon central structure | 兰州大学 | 2021-04-02 | — | — | CN | disclosed |
| CN-111233599-A | Aromatic ring ortho-iodoalkanone and synthetic method and application thereof | 兰州大学 | 2020-06-05 | — | — | CN | disclosed |
| EP-3515914-A1 | NOVEL 5 or 8-SUBSTITUTED IMIDAZO [1, 5-a]PYRIDINES AS SELECTIVE INHIBITORS OF INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | BeiGene, Ltd. (KY) | 2019-07-31 | — | — | EP | disclosed |
| CN-106632200-B | A kind of synthetic method of α-nitro cyclanone | 兰州大学 | 2019-05-28 | — | — | CN | disclosed |
| CN-109232149-A | A kind of synthetic method of the alpha-fluoro with fluorine-containing quaternary carbon center structure-alpha-substituted ketone | 兰州大学 | 2019-01-18 | — | — | CN | disclosed |
| WO-2018054365-A1 | NOVEL 5 or 8-SUBSTITUTED IMIDAZO [1, 5-a] PYRIDINES AS SELECTIVE INHIBITORS OF INDOLEAMINE AND/OR TRYPTOPHANE 2, 3-DIOXYGENASES | BEIGENE, LTD. (KY) | 2018-03-29 | — | — | WO | disclosed |
| CN-107338043-A | A kind of new racemic chirality organic boron nitrogen fluorescent chemicals and preparation method thereof | 湖南大学 | 2017-11-10 | — | — | CN | disclosed |
| CN-106632200-A | Synthesis method of alpha-nitrocycloalkanone | 兰州大学 | 2017-05-10 | — | — | CN | disclosed |
| WO-2014109712-A1 | PALLADIUM-CATALYZED ASYMMETRIC (HETERO)ARYLATION AND VINYLATION OF KETONE ENOLATES TO PRODUCE TERTIARY STEREOCENTERS AT ALPHA(α)-POSITION | NANAYNG TECHNOLOGICAL UNIVERSITY (SG) | 2014-07-17 | — | — | WO | disclosed |
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| US-7332260-B2 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | CORNING INCORPORATED (US) | 2008-02-19 | — | — | US | disclosed |
| EP-1119560-B1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING SA (FR) | 2003-03-05 | — | — | EP | disclosed |
| US-6506538-B1 | Ophthalmic lenses, contact lenses, solar protection glasses, filters, camera optics or photographic apparatus optics or other optical devices | CORNING S.A. (FR) | 2003-01-14 | — | — | US | disclosed |
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | BREYNE OLIVIER (FR) | 2002-12-26 | — | — | US | disclosed |
| CN-1315948-A | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO) polymer matrices containing them | CORNING SA (FR) | 2001-10-03 | — | — | CN | disclosed |
| EP-1119560-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | Corning S.A. (FR) | 2001-08-01 | — | — | EP | disclosed |
| WO-2000015628-A1 | NAPHTHOPYRANS ANNELATED IN C5-C6, THEIR PREPARATION AND COMPOSITIONS AND (CO) POLYMER MATRICES CONTAINING THEM | CORNING S.A. (FR) | 2000-03-23 | — | — | WO | disclosed |
| US-4187152-A | Extractive distillation for separating ketones and/or alcohols from phenol and/or cresol | ALLIED CHEMICAL CORPORATION (US) | 1980-02-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020197562-A1 | Naphthopyrans annelated in C5-C6, their preparation and compositions and (CO)polymer matrices containing them | C5, CCNC, C9 | IDO1 369/4885PLA2G6 1631/4885MAPT 2510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.