Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | RECQL | P46063 | 1/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | CFTR | P13569 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.44 |
| ▸ | CA1 | P00915 | 1/20 | 0.44 |
| ▸ | CA2 | P00918 | 1/20 | 0.44 |
| ▸ | CA7 | P43166 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29918942 | 1.00 | MAPT (0.51) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6674420 | 0.98 | MAPT (0.50) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL5740003 | 0.93 | KDM4E (0.52) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL69653 | 0.86 | MAPT (0.64) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL17276045 | 0.81 | MAPT (0.55) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL465841 | 0.80 | CYP1A2 (0.77) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29677764 | 0.80 | CYP1A2 (0.77) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL23037197 | 0.80 | MAPT (0.54) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| SCHEMBL29595815 | 0.80 | MAPT (0.54) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL6741600 | 0.79 | CYP1A2 (0.74) | MAPTCYP1A2SMN1; SMN2NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 607 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119039329-A | Binuclear rare earth complex, preparation method and application | 西安石油大学 | 2024-11-29 | — | — | CN | claimed |
| CN-111521601-B | Application of ratio-type fluorescent polymer hydrogel in seafood freshness detection | 中国科学院宁波材料技术与工程研究所 | 2022-01-25 | — | — | CN | claimed |
| CN-111808079-A | Indole ASK1 small molecule inhibitor and preparation method and application thereof | 中国药科大学 | 2020-10-23 | — | — | CN | claimed |
| CN-111521601-A | Application of ratio-type fluorescent polymer hydrogel in seafood freshness detection | 中国科学院宁波材料技术与工程研究所 | 2020-08-11 | — | — | CN | claimed |
| CN-109608441-A | A kind of synthesis technology of ASK1 inhibitor | 都创(上海)医药科技有限公司 | 2019-04-12 | — | — | CN | claimed |
| EP-4003988-B1 | 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS | SERVIER LAB (FR) | 2026-05-20 | — | — | EP | disclosed |
| EP-4096662-B1 | PROCESS FOR PREPARATION OF LASMIDITAN | ALIVUS LIFE SCIENCES LTD (IN) | 2026-03-25 | — | — | EP | disclosed |
| EP-4680607-A1 | BICYCLIC UREAS AS KINASE INHIBITORS | Incyte Corporation (US) | 2026-01-21 | — | — | EP | disclosed |
| WO-2025245472-A1 | COMPOUNDS AND RELATED METHODS USEFUL FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-11-27 | — | — | WO | disclosed |
| US-12466841-B2 | Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists | Nimbus Saturn, Inc. (US) | 2025-11-11 | — | — | US | disclosed |
| WO-2025226545-A1 | MODULATORS OF MITOCHONDRIAL DNA REPLICATION | PRETZEL THERAPEUTICS, INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| WO-2025227032-A1 | METHODS FOR DEGRADATION OF CYCLIN K AND INHIBITION OF CYCLIN DEPENDENT KINASES | REMIX THERAPEUTICS INC. (US) | 2025-10-30 | — | — | WO | disclosed |
| US-4689342-A | MITICIDES, NEMATOCIDES | ROUSSEL UCLAF (FR) | 1987-08-25 | — | — | US | disclosed |
| US-4596869-A | Pyridinyl and pyrimidinyl derivatives | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1986-06-24 | — | — | US | disclosed |
| EP-0110769-B1 | ESTERS DERIVED FROM 2,2-DIMETHYLCYCLOPROPANE-CARBOXYLIC ACIDS AND BIARYL ALCOHOLS, PROCESS FOR THEIR PREPARATION, THEIR USE AS PARASITICIDES AND COMPOSITIONS CONTAINING THEM | ROUSSEL-UCLAF (FR) | 1986-03-05 | — | — | EP | disclosed |
| US-4528296-A | Derivatives of aminopyridinecarboxylic acids and pharmaceutical compositions containing them | SIMES, SOCIETA ITALIANA MEDICINALLE SINTETICI (IT) | 1985-07-09 | — | — | US | disclosed |
| EP-0110484-A1 | Derivatives of aminopyridinecarboxylic acids, methods for their preparation and pharmaceutical compositions containing them | Simes S.p.A. (IT) | 1984-06-13 | — | — | EP | disclosed |
| US-4447256-A | POSTEMERGENCE HERBICIDE | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1984-05-08 | — | — | US | disclosed |
| US-4395411-A | ANTIBIOTICS; BACTERICIDES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1983-07-26 | — | — | US | disclosed |
| US-4267176-A | Amino or acylamino-substituted pyrimidinyl cephalosporanic acid derivatives and pharmaceutical compositions thereof | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1981-05-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12466841-B2 | Substituted pyrrolo[3,4-c]pyridines as HPK1 antagonists | PDXK, HIPK1, HIPK3 | MAPT 3393/4885CYP1A2 3917/4885SMN1; SMN2 3266/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.