Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC16A1 | P53985 | 17/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 8/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 7/20 | 0.54 |
| ▸ | SLC16A7 | O60669 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4797256 | 0.92 | SLC16A1 (0.60) | SLC16A1CYP2C9CYP3A4SLC16A7ALDH1A1 | |
| SCHEMBL4803047 | 0.91 | SLC16A1 (0.59) | SLC16A1CYP2C9CYP3A4SLC16A7ALDH1A1 | |
| SCHEMBL3828070 | 0.89 | SLC16A1 (0.72) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL4797275 | 0.88 | SLC16A1 (0.58) | SLC16A1CYP2C9CYP3A4SLC16A7ALDH1A1 | |
| SCHEMBL4797225 | 0.87 | SLC16A1 (0.59) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL4804234 | 0.85 | SLC16A1 (0.56) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL5138945 | 0.85 | SLC16A1 (0.56) | SLC16A1CYP2C9CYP3A4SLC16A7ALDH1A1 | |
| SCHEMBL4806350 | 0.84 | SLC16A1 (0.43) | SLC16A1CYP2C9CYP3A4SLC16A7ALDH1A1 | |
| SCHEMBL4845192 | 0.83 | SLC16A1 (0.69) | SLC16A1CYP2C9CYP3A4SLC16A7 | |
| SCHEMBL5099864 | 0.79 | SLC16A1 (0.62) | SLC16A1CYP2C9CYP3A4SLC16A7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080153855-A1 | Thieno[2,3-d]pyrimidinedione derivatives; antiproliferative agents against T-cells; chronic obstructive pulmonary disease, asthma; immunosuppressants, antihistamines, bronchodilator agents, and anticarcinogenic agents | ASTRAZENECA AB, A SWEDEN CORPORATION | 2008-06-26 | — | — | US | disclosed |
| US-7361660-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2008-04-22 | — | — | US | disclosed |
| US-20040171623-A1 | Chemical compounds | ASTRAZENECA AB (SE) | 2004-09-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080153855-A1 | Thieno[2,3-d]pyrimidinedione derivatives; antiproliferative agents against T-cells; chronic obstructive pulmonary disease, asthma; immunosuppressants, antihistamines, bronchodilator agents, and anticarcinogenic agents | HRH4, HRH2, HRH3 | SLC16A1 4716/4885CYP2C9 682/4885CYP3A4 397/4885 |
| US-20040171623-A1 | Chemical compounds | CBR1, SETDB1, CBR3 | SLC16A1 1397/4885CYP2C9 63/4885CYP3A4 60/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.